发明名称 |
PEPTIDE SUBSTANCE REVEALING A STRESS PROTECTIVE EFFECT, PHARMACEUTICAL COMPOSITION ON ITS BASE AND THE METHOD OF ITS APPLICATION |
摘要 |
The invention is related to the medicinal means of prevention and treatment for functional or stress induced disorders, which occur as a result of extreme impacts, and may be used as a medication revealing a stress protective effect. There is proposed a peptide glutamyl-aspartyl-glycine with general formula H-GIu- Asp-Gly-OH sequence 1 [SEQ ID NO:1], revealing a stress protective effect. There is proposed a pharmaceutical composition revealing a stress protective effect, characterized in that such composition contains an effective amount of peptide glutamyl- aspartyl-glycine with general formula H-GIu- Asp-Gly-OH sequence 1 [SEQ ID NO:1] as its active base, as well as a pharmaceutically acceptable carrier. In this case such pharmaceutical composition exists in the form suitable for parenteral or intranasal administration. There is proposed a method of prevention and/or treatment for functional or stress induced disorders, which occur as a result of extreme impacts, such method consisting in the administration to a patient of a pharmaceutical composition containing an effective amount of peptide glutamyl-aspartyl-glycine with general formula H-Glu-Asp-Gly-OH sequence 1 [SEQ ID NO:1] as its active base in the dose of 0,01 - 100 µg/kg of body weight, at least once a day during a period necessary for attaining a therapeutic effect. In this case such administration is performed parenterally or intranasally. |
申请公布号 |
WO2007136295(A2) |
申请公布日期 |
2007.11.29 |
申请号 |
WO2007RU00105 |
申请日期 |
2007.03.05 |
申请人 |
OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTYU "SIA PEPTIDES";KHAVINSON, VLADIMIR KHATSKELEVICH;GRIGORIEV, EVGENY IOSIFOVICH;MALININ, VLADIMIR VICTOROVICH;RYZHAK, GALINA ANATOLIEVNA |
发明人 |
KHAVINSON, VLADIMIR KHATSKELEVICH;GRIGORIEV, EVGENY IOSIFOVICH;MALININ, VLADIMIR VICTOROVICH;RYZHAK, GALINA ANATOLIEVNA |
分类号 |
C07K14/43 |
主分类号 |
C07K14/43 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|