发明名称 |
A GENERAL METHOD FOR GENERATING HUMAN ANTIBODY RESPONSES IN VITRO |
摘要 |
This invention relates to an in vitro method of producing antigen specific B cells and antibodies that provides for the capture of an entire primary human antibody repertoire for any foreign antigen, allows for screening large numbers of immunogen/adjuvant combinations, and permits the isolation of human monoclonal antibodies on demand thereby obviating the need to immunize humans with the target antigen. |
申请公布号 |
WO2007134220(A2) |
申请公布日期 |
2007.11.22 |
申请号 |
WO2007US68752 |
申请日期 |
2007.05.11 |
申请人 |
UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE;LEWIS, GEORGE K.;GUAN, YONGJUN |
发明人 |
LEWIS, GEORGE K.;GUAN, YONGJUN |
分类号 |
A61M25/06;C12N5/0781;C12N5/0784 |
主分类号 |
A61M25/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|