| 发明名称 |
ANTIBODIES TO UROKINASE- TYPE PLASMINOGEN ACTIVATOR RECEPTOR(UPAR)BIND CANCER STEM CELLS: USE IN DIAGNOSIS AND THERAPY |
| 摘要 |
<p>Cancer or tumor stem cells (CaSCs) express urokinase-type plasminogen activator receptor (uPAR) on their surfaces. Ligands of uPAR, in particular antibodies are used to bind, detect, inactivate or purge uPAR-expressing cancer stem cells. Such antibodies or other ligands are also used in methods for diagnosing and treating cancer.</p> |
| 申请公布号 |
WO2007134274(A2) |
申请公布日期 |
2007.11.22 |
| 申请号 |
WO2007US68845 |
申请日期 |
2007.05.14 |
| 申请人 |
ATTENUON, LLC;MAZAR, ANDREW, P. |
发明人 |
MAZAR, ANDREW, P. |
| 分类号 |
A61K49/10 |
主分类号 |
A61K49/10 |
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