发明名称 AGENT FOR INHIBITING GROWTH OF NEOPLASM IN MAMMAL
摘要 PROBLEM TO BE SOLVED: To provide an agent for the treatment of neoplastic diseases having broad spectrum including sarcoma, fibrosarcoma, glioblastoma, malignant tumor, melanoma, Hodgkin's lymphoma, non-Hodgkin's lymphoma, leukemia and other neoplastic symptoms. SOLUTION: The invention relates to an agent for inhibiting the growth of neoplasm in mammals by using a prolactin modifying agent and a prolactin promoting agent. The prolactin modifying agent is administered to mammals at a prescribed time within 24 hour period to coincide or approach the circadian prolactin profile of the mammals to the circadian prolactin profile of healthy mammals of the same species and sex, and the prescribed time is determined by comparing the prolactin level of the blood of the mammals at multiple discrete timings within the 24 hour period with the corresponding blood prolactin level in a daily baseline prolactin profile of healthy mammals of the same species and sex. COPYRIGHT: (C)2008,JPO&INPIT
申请公布号 JP2007302701(A) 申请公布日期 2007.11.22
申请号 JP20070215913 申请日期 2007.08.22
申请人 BOARD OF SUPERVISORS OF LOUISIANA STATE UNIV & AGRICULTURAL & MECHANICAL COLLEGE;GENERAL HOSPITAL CORP DOING BUSINESS AS MASSACHUSETTS GENERAL HOSPITAL 发明人 MEIER ALBERT H;CINCOTTA ANTHONY H
分类号 A61K45/00;A61K31/165;A61K31/166;A61K31/40;A61K31/4045;A61K31/405;A61K31/445;A61K31/454;A61K31/48;A61K38/22;A61K45/06;A61P35/00;A61P43/00;C07D519/02 主分类号 A61K45/00
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