发明名称 |
Contrast Agents Endowed with High Relaxivity for Use in Magnetic Resonance Imaging (Mri) Which Contain a Chelating Moiety with Polyhydroxylated Substituents |
摘要 |
The present invention relates to a new class of paramagnetic ion-based contrast agents of molecular weight lower than 3.5 kDa that show a pharmacokinetic profile analogous to that of the commonly used T1-general extravascular agents and that are further characterized by a higher relaxivity.
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申请公布号 |
US2007258905(A1) |
申请公布日期 |
2007.11.08 |
申请号 |
US20050630605 |
申请日期 |
2005.06.28 |
申请人 |
BRACCO IMAGING SPA |
发明人 |
AIME SILVIO;GALLI MATTEO;LATTUADA LUCIANO;MOROSINI PIERFRANCESCO;UGGERI FULVIO;RAMALINGAM KONDAREDDIAR |
分类号 |
A61B5/055;A61K49/06;A61K49/10;C07C211/00;C07C229/76;C07D211/00;C07D233/02;C07D243/00;C07D243/08;C07D255/04;C07D257/02;C07D315/00;C07D401/14;C07D405/14;C07F9/02;G01N24/08 |
主分类号 |
A61B5/055 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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