<p>Controlled release tolterodine beads are formed of a sugar core, an innermost sealcoat layer comprising HPMC, a tolterodine drug layer, and an outer control release layer. The thickness of the hydrophilic HPMC sealcoat layer can be used help modulate the release of the tolterodine drug.</p>
申请公布号
WO2007122015(A1)
申请公布日期
2007.11.01
申请号
WO2007EP03728
申请日期
2007.04.20
申请人
SYNTHON B.V.;VAN DEN HEUVEL, DENNIE, JOHAN, MARIJN