发明名称 |
COPPER-MEDIATED FUNCTIONALIZATION OF ARYL C-H BONDS, AND COMPOUNDS RELATED THERETO |
摘要 |
<p>One aspect of the present invention relates to methods for direct functionalization of pyridyl-substituted aromatic compounds. In certain embodiments, 2-arylpyridine substrates react with anionic nucleophiies in the presence of copper(II) to furnish substituted arylpyridines. In other embodiments, the present invention allows for both mono- and di- functionalizations from manipulation of the reaction conditions. The transition metal- mediated carbon-heteroatom bond-forming methods are applicable to a variety of synthetic transformations of aryl C-H bonds.</p> |
申请公布号 |
WO2007123910(A2) |
申请公布日期 |
2007.11.01 |
申请号 |
WO2007US09382 |
申请日期 |
2007.04.18 |
申请人 |
BRANDEIS UNIVERSITY;YU, JIN-QUAN |
发明人 |
YU, JIN-QUAN |
分类号 |
C07D213/57 |
主分类号 |
C07D213/57 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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