siRNA SPECIFIC TO WT1 17AA(-)ISOFORM AND USE THEREOF

摘要

Disclosed is a polynucleotide which comprises contiguous at least 15 nucleotides in the nucleotide sequence depicted in SEQ ID NO:26 and contains the nucleotide sequence depicted in SEQ ID NO:27. Also disclosed is siRNA produced based on the polynucleotide. A cancer cell-specific molecular-targeting therapy which can successfully control the function of WT1 can be realized.