摘要 |
The present invention provides for compositions and methods for recognizing toxins in a host. The composition comprising a particle of less than 100 micrometers in diameter having a tag in direct contact with a portion of the particle, the particle comprising a biodegradable polymer and the portion of the particle in contact with the tag selected from the group consisting of acrylic acid, 2-hydroxyethyl acrylate, 2-acrylamido-2-methyl-1-propanesulfonic acid, allylamine, carboxyl group, hydroxyl group, sulfonic group, aldehyde group, and amine group, wherein the tag is selected from the group consisting of drug, antibody, ligand, antigen, protein, peptide, counter-ligand moiety, fatty acid moiety, and carbohydrate moiety, and wherein one or more particles are introduced into the host having toxins and the one or more particle recognize the toxins.
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