发明名称 |
Nanoparticle vaccines |
摘要 |
The present invention relates to nanoparticle vaccines comprised of a carrier, particularly polymerized lipids, having multiple copies of an antigen or combinations of different antigens displayed on the carrier. Such antigen-displaying nanoparticles may also display a targeting molecule on its surface in order to direct it to a specific site or cell type to optimize a desired immune response. The present invention also relates to encapsulating an antigen or combinations of different antigens within such nanoparticles, with or without a targeting molecule displayed on its surface. The antigens used in this invention are effective to produce an immune response against a variety of pathological conditions.
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申请公布号 |
US7285289(B2) |
申请公布日期 |
2007.10.23 |
申请号 |
US20030413607 |
申请日期 |
2003.04.14 |
申请人 |
NAGY JON O;BARGATZE ROBERT F;JUTILA JOHN W;CUTLER JIM E;GLEE PATI M |
发明人 |
NAGY JON O.;BARGATZE ROBERT F.;JUTILA JOHN W.;CUTLER JIM E.;GLEE PATI M. |
分类号 |
A61K39/00;A61B5/055;A61K9/00;A61K9/127;A61K9/14;A61K39/145;A61K39/38;A61K49/00 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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