发明名称 |
Dendrite Cells Transduced with Recombinant Adenovirus Advcea Which Generate Cea-Specific Cytotoxic T Lymphocytes, Vaccine and Pharmaceutical Composition Comprising the Same |
摘要 |
The present invention relates to an antitumor immune response, and in more detail, to a method for inducing cytotoxic T lymphocytes specific to a tumor-associated antigen that acts specifically on tumor cells. Immunotherapy using the present invention may be most effective among immune therapies that use immunity of our body, because in the present invention, CEA-specific cytotoxic T lymphocytes can be induced in vitro by using a dendritic cell transduced with a recombinant adenovirus. Further, immunotherapy using the present invention can function as a powerful tool for tumor prevention or treatment, if being used in combination with antitumor vaccines or other treatments.
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申请公布号 |
US2007243197(A1) |
申请公布日期 |
2007.10.18 |
申请号 |
US20070570282 |
申请日期 |
2007.02.23 |
申请人 |
KIM TAI-GYU;CHO HYUN-IL;KIM HYE-JIN;OH SEOUG-TAEK |
发明人 |
KIM TAI-GYU;CHO HYUN-IL;KIM HYE-JIN;OH SEOUG-TAEK |
分类号 |
A61K39/00;A61K39/235;A61K48/00;C07K14/705;C12N5/16;C12N7/01 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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