| 摘要 |
<p>The invention provides a process for the manufacture of H1 6 dimethanesulfonate comprising contacting an O-protected pyridine aldoxime compound with bis(methylsulphonoxymethyl)ether in a suitable solvent to form an intermediate compound, contacting said intermediate compound with isonicotinamide to form an O-protected HI 6 product precursor, and de-protecting the precursor to form HI 6 dimethanesulfonate.</p> |
