| 摘要 |
<p>The present invention provides compounds of formula (I), their use as an inhibitor of a p53-MDM2 interaction as well as pharmaceutical compositions comprising said compounds of formula (I) wherein n, m, p, t, R<SUP>1</SUP> , R<SUP>2</SUP> , R<SUP>3</SUP>, R<SUP>4</SUP>, R<SUP>5</SUP>, R<SUP>6</SUP>, R<SUP>7</SUP>, Q, Y and Z have defined meanings.</p> |
| 申请人 |
JANSSEN PHARMACEUTICA N.V.;LACRAMPE, JEAN, FERNAND, ARMAND;MEYER, CHRISTOPHE;SCHOENTJES, BRUNO;PONCELET, ALAIN, PHILIPPE;WERMUTH, CAMILLE, GEORGES;GIETHLEN, BRUNO;CONTRERAS, JEAN-MARIE;JOUBERT, MURIEL;VAN HIJFTE, LUC |
发明人 |
LACRAMPE, JEAN, FERNAND, ARMAND;MEYER, CHRISTOPHE;SCHOENTJES, BRUNO;PONCELET, ALAIN, PHILIPPE;WERMUTH, CAMILLE, GEORGES;GIETHLEN, BRUNO;CONTRERAS, JEAN-MARIE;JOUBERT, MURIEL;VAN HIJFTE, LUC |
