发明名称 |
FORMULATIONS FOR A TIGHT JUNCTION EFFECTOR |
摘要 |
Enteric compositions comprising one or more tight junction agonists and/or one or more tight junction antagonists are provided. Compositions of the invention may comprise a delayed-release coating disposed over a tight junction agonist and/or tight junction antagonist layer which may be disposed over an inert core. Delayed-release coatings may be substantially stable in gastric fluid and substantially unstable in intestinal fluid, thus providing for substantial release of the tight junction agonist and/or antagonist from the composition in the duodenum or jejunum of the small intestine.
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申请公布号 |
US2007196501(A1) |
申请公布日期 |
2007.08.23 |
申请号 |
US20070673342 |
申请日期 |
2007.02.09 |
申请人 |
ALBA THERAPEUTICS CORP. |
发明人 |
PATERSON BLAKE;GINSKI MARK J. |
分类号 |
A61K38/08;A61K9/16;A61K9/50;A61K31/175;A61K31/426;A61K38/28 |
主分类号 |
A61K38/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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