ASSAYS AND ENHANCERS OF THE HUMAN DELTA ENAC SODIUM CHANNEL
摘要
This invention relates to electrophysiological assays that measure sodium conductance activity of a delta human epithelial sodium channel (ENaC) in the presence and absence of delta hENaC enhancers. Also, the invention generally relates to assays for identifying compounds that enhance the activity of delta hENaC, especially in an oocyte expression system. These compounds have potential application in modulating (enhancing) salty taste perception.
申请公布号
WO2007092185(A2)
申请公布日期
2007.08.16
申请号
WO2007US02293
申请日期
2007.01.26
申请人
SENOMYX, INC.;MOYER, BRYAN;LU, MIN;ECHEVERRI, FERNANDO