发明名称 |
COMPOSITIONS WITH ANTIGENS ADSORBED TO CALCIUM PHOSPHATE |
摘要 |
Calcium phosphate is used as an adjuvant, with a high degree of antigen adsorption to the adjuvant. The invention is particularly useful for adjuvanting conjugated capsular saccharide antigens. Buffers, such as phosphate or histidine buffers, can advantageously be used in combination with the calcium phosphate, and compositions may have a pH in the range of 5.5 to 7.5. |
申请公布号 |
WO2007053781(A3) |
申请公布日期 |
2007.08.09 |
申请号 |
WO2006US43162 |
申请日期 |
2006.11.01 |
申请人 |
NOVARTIS AG;CONTORNI, MARIO;SINGH, MANMOHAN;O'HAGAN, DEREK |
发明人 |
CONTORNI, MARIO;SINGH, MANMOHAN;O'HAGAN, DEREK |
分类号 |
A61K39/02;A61K39/095 |
主分类号 |
A61K39/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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