发明名称 Polynucleotides encoding three novel human cell surface proteins with leucine rich repeats and immunoglobulin folds, BGS2, 3 and 4 and variants thereof
摘要 The present invention provides novel polynucleotides encoding BGS-2, 3, and 4 polypeptides, fragments and homologues thereof Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-2, 3, and 4 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
申请公布号 US2007178088(A1) 申请公布日期 2007.08.02
申请号 US20070726220 申请日期 2007.03.21
申请人 BRISTOL-MYERS SQUIBB COMPANY 发明人 WU SHUJIAN;KRYSTEK STANLEY R.JR.;LEE LIANA;FEDER JOHN N.;CHENG JANET D.
分类号 A61K39/395;A61K38/00;A61K38/17;C07H21/04;C07K14/705;C07K16/28;C12N5/08;C12P21/06;G01N33/53 主分类号 A61K39/395
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