发明名称 |
SUBSTITUTED BICYCLIC 8-PYRR0LIDINOXANTHINES, METHODS FOR THEIR PRODUCTION, PHARMACEUTICAL FORMULATIONS AND THEIR USE |
摘要 |
Compounds for the treatment of elevated blood glucose levels and the physiological and metabolic disorders arising therefrom are disclosed and comprise novel substituted bicyclic 8-pyrrolidinoxanthines and their derivatives of formula l: wherein the various R groups are hereinafter defined. The present invention also comprises pharmaceutical compositions comprising them as well as processes for the preparation of these compounds. Particular blood glucose disorders treatable thereby include type-2 diabetes, insulin resistance, hyperglycemia, arteriosclerotic diseases and the like.
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申请公布号 |
US2007167468(A1) |
申请公布日期 |
2007.07.19 |
申请号 |
US20070623770 |
申请日期 |
2007.01.17 |
申请人 |
SANOFI-AVENTIS DEUTSCHLAND GMBH |
发明人 |
SCHOENAFINGER KARL;JAEHNE GERHARD;DEFOSSA ELISABETH;SCHWINK LOTHAR;WAGNER HOLGER;BUNING CHRISTIAN;TSCHANK GEORG;WERNER ULRICH |
分类号 |
A61K31/522;C07D473/04;C07D519/00 |
主分类号 |
A61K31/522 |
代理机构 |
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地址 |
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