发明名称 |
Sich selbst-zusammenbauende Rekombinante HPV16 Papillomavirus Hüllproteine |
摘要 |
<p>Recombinant papillomavirus capsid proteins that are capable of self-assembly into capsomer structures and viral capsids that comprise conformational antigenic epitopes are provided. The capsomer structures and viral capsids, consisting of the capsid proteins that are expression products of a bovine, monkey or human papillomavirus L1 conformational coding sequence proteins, can be prepared as vaccines to induce a high-titer neutralizing antibody response in vertebrate animals. The self assembling capsid proteins can also be used as elements of diagnostic immunoassay procedures for papillomavirus infection.</p> |
申请公布号 |
DE122007000028(I1) |
申请公布日期 |
2007.07.12 |
申请号 |
DE20071200028C |
申请日期 |
1993.09.03 |
申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA ASREPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH |
发明人 |
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分类号 |
C07K14/025;G01N33/53;A61K39/00;A61K39/12;A61K39/23;A61P17/12;A61P31/12;A61P31/20;A61P35/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N7/04;C12N15/09;C12N15/37;C12P21/02;C12Q1/70;C12R1/91;G01N33/566;G01N33/569 |
主分类号 |
C07K14/025 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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