发明名称 |
Acyl CoA:cholesterol acyltransferase (ACAT-2) |
摘要 |
Nucleic acid compositions encoding novel ACAT proteins, as well as the novel ACAT-2 proteins, (ACAT-2) are provided. Also provided are methods of producing the subject nucleic acid and protein compositions. The subject polypeptide and nucleic acid compositions find use in a variety of applications, including diagnostic and therapeutic agent screening applications, as well as in treatment therapies for disease conditions associated with ACAT-2 activity, e.g., in the treatment of gall stones.
|
申请公布号 |
US7238779(B2) |
申请公布日期 |
2007.07.03 |
申请号 |
US20040779251 |
申请日期 |
2004.02.12 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
CASES SYLVAINE;FARESE, JR. ROBERT V.;ERICKSON SANDRA K.;NOVAK SABINE;ACCAD MICHEL |
分类号 |
C07K1/00;A61K38/00;A61K38/16;C07K14/00;C07K17/00;C12N9/10;C12N15/09;C12Q1/48 |
主分类号 |
C07K1/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|