HYDANTOINS WITH INSULINOTROPIC ACTION

摘要

The present invention relates to a hydantoin of general formula I in which R<SUB>1</SUB> and R<SUB>2</SUB> represent, independently of one another, a C<SUB>1</SUB>-C<SUB>6</SUB>-alkyl group, an aryl group or an aralkyl group; R<SUB>3</SUB> and R<SUB>4</SUB> represent, independently of one another, a hydrogen atom, a C<SUB>1</SUB>-C<SUB>6</SUB>-alkyl group, an aryl group or an aralkyl group; or, in the case where R<SUB>4</SUB> represents a hydrogen atom: its tautomeric form of general formula Ia in which R<SUB>1</SUB>, R<SUB>2</SUB> and R<SUB>3</SUB> are as defined in general formula I, or its tautomeric form of general formula in which R<SUB>1</SUB>, R<SUB>2</SUB> and R<SUB>3</SUB> are as defined in general formula I, or pharmaceutically acceptable addition salts, isomers, enantiomers and diastereoisomers thereof, and mixtures thereof. It also relates to a process for the preparation thereof and to the use thereof in the treatment of diabetes.