发明名称 |
Inhibitors of serine proteases, particularly HCV NS3-NS4A protease |
摘要 |
The present invention relates to compounds of formula: (I) or a pharmaceutically acceptable salt or mixtures thereof that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection and to processes for preparing the compounds. The invention also relates to methods of treating anHCV infection in a patient by administering a composition comprising a compound of this invention. The invention further relates to processes for preparing these compounds. |
申请公布号 |
ZA200602937(B) |
申请公布日期 |
2007.06.27 |
申请号 |
ZA20060002937 |
申请日期 |
2004.10.08 |
申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
COTTRELL, KEVIN M;PERNI, ROBERT B;PITLIK, JANOS |
分类号 |
A61K;C07K |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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