USE OF EFFECTOR-FUNCTION-DEFICIENT ANTIBODIES FOR TREATMENT OF AUTO-IMMUNE DISEASES
摘要
<p>The invention relates to the treatment of autoimmune diseases and disorders, in particular myasthenia gravis, by administration of effector-function-deficient antibodies, wherein said effector-function-deficient antibodies are capable of competing with one or more of the auto-antibodies involved in mediating the antibody-mediated auto-immune disease or disorder for binding to a target auto-antigen.</p>
申请公布号
WO2007068255(A1)
申请公布日期
2007.06.21
申请号
WO2006DK00719
申请日期
2006.12.15
申请人
GENMAB A/S;LOSEN, MARIO;MARTINEZ-MARTINEZ, PILAR;DE BAETS, MARC H.;GRAUS, YVO;SCHUURMAN, JANINE;PARREN, PAUL
发明人
LOSEN, MARIO;MARTINEZ-MARTINEZ, PILAR;DE BAETS, MARC H.;GRAUS, YVO;SCHUURMAN, JANINE;PARREN, PAUL