| 摘要 |
The invention relates to an improved process for the synthesis of 13-(N-Boc-beta-isobutylserinyl)-14-beta-hydroxybaccatin III-1,14-carbonate (I), wherein carbonation of the 1,14-hydroxy groups of the baccatin skeleton is carried out with bis(trichloromethylcarbonate and the 7-hydroxy group is protected with a trichloroacetyl group.
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