| 摘要 |
PROBLEM TO BE SOLVED: To provide a neovascular material which can directly inject a neovascularization-promoting ingredient having a neovascular action into subcutaneous tissues or muscular tissues, and to provide a method for producing the same. SOLUTION: This neovascular material comprising a gel formed by irradiating and cross-linking at least a neovascularization-promoting ingredient and a photo-sensitive group-introduced gelatin modified product with light, and the method for producing the same is characterized in that the neovascularization-promoting ingredient is a compound having 1-benzyl-4-[1-indanon-2-yl]methylpiperidine as a basic structure and/or its salt, wherein the compound has a substituent selected from the group consisting of carboxyl group, alkyl group, halogen atom, hydrogen atom, alkoxy group, amino group, OH, thiol group and aldehyde group at least at one place among the 5-position or 6-position of the 1-indanone and the 3-position, 4-position or 5-position of the benzene nucleus of the 1-benzylpiperidine. COPYRIGHT: (C)2007,JPO&INPIT
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