| 摘要 |
<p>The present invention provides nucleic acids, proteins and vectors for a method of nucleic acid, including DNA, immunization of a host, including humans, against disease caused by infection by a strain of <Italic>Chlamydia,</Italic> specifically <Italic>C</Italic>. <Italic>pneumoniae</Italic>. The method employs a vector containing a nucleotide sequence encoding a polypeptide of a strain of <Italic>Chlamydia pneumoniae</Italic> operably linked to a promoter to effect expression of the gene product in the host. The polypeptides are derived from <Italic>C</Italic>. <Italic>pneumoniae</Italic> and are selected from an ATP-binding cassette protein, a secretory locus ORF, an endopeptidase, a protease, a metalloprotease, CLP protease ATPase, a CLP protease subunit, a translycolase/transpeptidase, a CLPc protease and thioredoxin.</p> |
