METHODS FOR SYNTHESIS OF 3-AMINO-1-ARYLPROPYL INDOLES

摘要

A method comprising: hydrogenating an indole propionamide compound of formula h with vitride, to form an aminopropyl indole compound of formula I wherein m, Ar, R<SUP>1</SUP> and R<SUP>2</SUP> are as defined herein. The compounds prepared by the method of the invention are useful as monoamine reuptake inhibitors useful for treatment of CNS indications.