发明名称 |
Glycosaminoglycan/collagen complexes and use thereof |
摘要 |
The present invention is intended to offer a novel material which combines cell-adhesive proteins such as collagen with GAG polymers to construct an environment similar to an extracellular matrix, capable of controlling differentiation and proliferation of cells. The present invention offers a glycosaminoglycan-functionalized polymer protein composite produced by combining a cell-adhesive protein with a glycosaminoglycan-functionalized polymer obtained by incorporating a carbohydrate chain containing a structure corresponding to at least a portion of a glycosaminoglycan backbone into a vinyl polymer main chain, as well as a cell culture substrate and a material for tissue reconstruction treatments comprising the composite.
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申请公布号 |
US7226611(B2) |
申请公布日期 |
2007.06.05 |
申请号 |
US20040472347 |
申请日期 |
2004.02.12 |
申请人 |
YAIZU SUISANKAGAKU INDUSTRY CO., LTD. |
发明人 |
YURA HIROFUMI;ISHIHARA MASAYUKI;SAITO YOSHIO;ONO KATSUAKI;SATO MASATO |
分类号 |
A61F2/02;A61K31/726;A61K31/727;A61K38/39;A61K47/36;A61K47/42;A61L27/26;A61L27/48;A61P43/00;C08B37/00;C08H1/06;C08L5/08;C08L5/10;C12M3/00;C12N5/00 |
主分类号 |
A61F2/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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