摘要 |
The present invention is directed to the preparation of novel compounds useful in the treatment of hyperlipidemia, arteriosclerosis, hypercholesterolemia, and other related metabolic disorders. More specifically, the present invention is a novel process for the preparation of 1,4-diphenylazetidinone derivatives from beta-substituted amino amides which are protected in the presence of silylating agents and at least one cyclization catalyst whose structural formula is represented by one of the general formula: wherein the various R-groups are defined herein. |
申请人 |
SANOFI-AVENTIS DEUTSCHLAND GMBH |
发明人 |
LINDENSCHMIDT, ANDREAS;WILL, DAVID, WILLIAM;JAEHNE, GERHARD;JENDRALLA, HEINER;WOLLMANN, THEODOR, ANDREAS;FRICK, WENDELIN;JUNKER, BERND;RIGAL, DAVID;BILLEN, GUENTER |