发明名称 |
Pyrazole compositions useful as inhibitors of glycogen synthase kinase-3 (GSK-3) |
摘要 |
A compound of formula (I) or a pharmaceutically acceptable derivative thereof is disclosed, wherein the variables are as defined in the specification. These compounds are inhibitors of protein kinases, particularly inhibitors of GSK3 mammalian protein kinase. Pharmaceutically acceptable compositions comprising these compounds and methods of utilizing those compounds and compositions in the treatment of various protein kinase mediated disorders are also described.
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申请公布号 |
NZ538426(A) |
申请公布日期 |
2007.05.31 |
申请号 |
NZ20030538426 |
申请日期 |
2003.07.31 |
申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
FORSTER, CORNELIA J;PARK, LARRY C;WANNAMAKER, MARION W;YAO, YUNG-MAE |
分类号 |
A61K31/506;A61K31/5377;A61K45/00;A61P3/10;A61P9/00;A61P9/02;A61P11/06;A61P17/14;A61P25/00;A61P25/16;A61P25/18;A61P25/24;A61P25/28;A61P27/06;A61P29/00;A61P37/06;A61P43/00;C07D403/12;C07D471/04;(IPC1-7):C07D471/04;A61K31/442;A61K31/415 |
主分类号 |
A61K31/506 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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