METHODS OF TREATING FIBROSING DISEASES BY INDUCTION OF IMMUNE TOLERANCE
摘要
<p>The present invention has demonstrated for the first time that orally administered type I collagen (CI) induced tolerance to CI in patients suffering from systemic sclerosis (SSc) and ameliorated clinical manifestations of the disease. Accordingly, the present invention provides methods of treating a fibrosing disease by oral administration of a tissue protein, for example, collagen, derived from the tissue undergoing fibrosis.</p>
申请公布号
WO2007059211(A2)
申请公布日期
2007.05.24
申请号
WO2006US44344
申请日期
2006.11.16
申请人
THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION;POSTLETHWAITE, ARNOLD, E.;KANG, ANDREW, H.