SINGLE NUCLEOTIDE POLYMORPHISMS IN THE CKRX GENE ASSOCIATED WITH RESPIRATORY DISEASE

摘要

The present invention relates to single nucleotide polymorphisms in the CKRX gene and their association with respiratory diseases such as asthma. The present invention also relates to the identification of corresponding haplotypes and their association with respiratory diseases such as asthma. Thus, the present invention also identifies a role for CKRX in human disorders where previously its function was unknown. In this regard, the present invention also provides methods and assays for identifying compounds which interact with CKRX and which may be used for treating respiratory diseases.