发明名称 HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF
摘要 <p>Disclosed is a FXR inhibitor comprising a compound represented by the formula (I') or a salt or a prodrug of the compound or salt: wherein each symbol is as defined in the description. The FXR inhibitor has an excellent FXR-inhibiting effect, can significantly decrease the blood LDL-cholesterol level or the blood non-HDL-cholesterol level, and exerts an effect of decreasing the triglyceride level, an effect of increasing the HDL-cholesterol level and an effect of promoting the excretion of bile acid into the feces.</p>
申请公布号 WO2007052843(A1) 申请公布日期 2007.05.10
申请号 WO2006JP322420 申请日期 2006.11.02
申请人 TAKEDA PHARMACEUTICAL COMPANY LIMITED;MIURA, SHOTARO;SHIMADA, MITSUYUKI;MARUI, SHOGO;TAMURA, NORIKAZU;NAKADA, YOSHIHISA;TOZAWA, RYUICHI;SAKAMOTO, JUNICHI;FUNABASHI, YASUNORI;HOSONO, HIROSHI 发明人 MIURA, SHOTARO;SHIMADA, MITSUYUKI;MARUI, SHOGO;TAMURA, NORIKAZU;NAKADA, YOSHIHISA;TOZAWA, RYUICHI;SAKAMOTO, JUNICHI;FUNABASHI, YASUNORI;HOSONO, HIROSHI
分类号 A61K31/4178;C07D207/34;A61K31/381;A61K31/40;A61K31/415;A61K31/4155;A61K31/4184;A61K31/42;A61K31/422;A61K31/4245;A61K31/427;A61K31/454;A61K31/4709;A61K31/496;A61K31/506;A61K31/5377;A61K31/541;A61K31/553;A61P3/06;A61P9/10;A61P43/00;C07D213/81;C07D213/82;C07D231/14;C07D233/90;C07D239/28;C07D261/18;C07D263/34;C07D277/20;C07D277/56;C07D307/68;C07D333/38;C07D401/04;C07D401/12;C07D401/14;C07D403/12;C07D409/12;C07D413/12;C07D413/14;C07D417/12;C07D417/14;C07D487/04;C07D498/04 主分类号 A61K31/4178
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