Post-translational modification, including protein methylation, plays an important role in regulating protein function. The present invention provides a novel assay for evaluating demethylase activity and the discovery of a family of protein demethylases comprising a novel demethylase motif.
申请公布号
WO2007053480(A2)
申请公布日期
2007.05.10
申请号
WO2006US42126
申请日期
2006.10.27
申请人
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL;ZHANG, YI;TSUKADA, YUICHI;YAMANE, KENICHI;KLOSE, ROBERT JOHN
发明人
ZHANG, YI;TSUKADA, YUICHI;YAMANE, KENICHI;KLOSE, ROBERT JOHN