发明名称 |
PROCESS FOR PREPARATION OF OPTICALLY ACTIVE SULFONAMIDES AND INTERMEDIATES FOR THEIR SYNTHESIS |
摘要 |
A method including resolution of a diastereomeric mixture represented by the formula <CHEM> wherein R<1> and R<2> are the same or different and each is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, only one of R<1> and R<2> contains one asymmetric carbon, and R<a> is an optically active and optionally substituted hydrocarbon group or an optically active and optionally substituted heterocyclic group, or a salt thereof, to produce the diastereomer having a steric configuration of the asymmetric carbon for R<1> or R<2> of an R configuration or an S configuration, or a salt thereof. |
申请公布号 |
EP1334966(A4) |
申请公布日期 |
2007.04.18 |
申请号 |
EP20010976719 |
申请日期 |
2001.10.17 |
申请人 |
TAKEDA PHARMACEUTICAL COMPANY LIMITED |
发明人 |
IKEMOTO, TOMOMI;NISHIGUCHI, ATSUKO;TOMIMATSU, KIMINORI |
分类号 |
C07C303/40;C07B57/00;C07C303/44;C07C311/14;C07C311/51 |
主分类号 |
C07C303/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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