发明名称 AMINE COMPOUND AND USE THEREOF
摘要 PROBLEM TO BE SOLVED: To provide new amine compounds which are efficacious against diseases such as a viral infectious disease with HIV, rheumatism, and cancer metastasis. SOLUTION: The invention relates to the amine compounds which are represented by the general formula (1) or pharmacologically acceptable salts thereof. [A<SB>1</SB>and A<SB>2</SB>are each independently (substituted) imidazole group, at least one is N-(carboxylmethyl)imidazole or N-(ethoxycarbonylmethyl)imidazole. W is a (substituted)benzene ring. X is CH<SB>2</SB>. D is a group represented by formula (6).]. [Q is CH<SB>2</SB>, NR<SB>12</SB>, R<SB>12</SB>is H or methyl group in the formula (6). Y is a group represented by formula (7)]. [m<SB>3</SB>is an integer of 0-6. R<SB>18</SB>, R<SB>19</SB>are each H in the formula (7). B is a group represented by formula (8)]. [R<SB>25</SB>, R<SB>26</SB>are each a (substituted) 1-15C alkyl group in the formula (8)]. COPYRIGHT: (C)2007,JPO&INPIT
申请公布号 JP2007091755(A) 申请公布日期 2007.04.12
申请号 JP20070001425 申请日期 2007.01.09
申请人 KUREHA CORP 发明人 SAITO ATSUYUKI;KIKUMOTO NARIYUKI;ONO MASAHIRO;MATSUI MAKOTO;YAMAMOTO MASASHI;SAWA TOMOHIRO;SUZUKI SHIGERU;YANAKA MIKIRO
分类号 C07D233/64;A61K31/417;A61K31/4178;A61K31/4184;A61K31/428;A61K31/4439;A61K31/454;A61K31/4709;A61K31/4725;A61K31/5377;A61K31/5513;A61P29/00;A61P31/18;A61P35/00;A61P43/00;C07D401/12;C07D401/14;C07D403/14;C07D405/14;C07D417/14;C07D471/04 主分类号 C07D233/64
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