发明名称 |
Influensaoverflateantigenvaksine samt fremgangsmate for a fremstille nevnte vaksine. |
摘要 |
<p>The present invention is concerned with an Influenza surface antigen vaccine obtainable by production from Influenza Viruses propagated on animal cell culture and having a host cell DNA content equal to or less than 25 pg per dose. The present invention is also concerned with a method for the preparation of surface antigen proteins from Influenza Viruses propagated on an animal cell culture comprising the subsequent steps of: a. treatment of the whole virus containing fluid obtained from the cell culture with a DNA digesting enzyme, and b. adding a cationic detergent, followed by isolation of the surface antigen proteins.</p> |
申请公布号 |
NO323349(B1) |
申请公布日期 |
2007.04.02 |
申请号 |
NO19980001557 |
申请日期 |
1998.04.06 |
申请人 |
DUPHAR INTERNATIONAL RESEARCH BV |
发明人 |
SCHARRENBURG GUSTAAF JOHAN MARIE VAN;BRANDS RUDI |
分类号 |
A61K39/145;C12P21/00;A61K35/76;A61P31/12;A61P31/16;A61P37/00;C07K1/14;C07K14/11;C12N7/00;C12N7/02;C12N7/04 |
主分类号 |
A61K39/145 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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