摘要 |
PROBLEM TO BE SOLVED: To provide a medicine for treating nervous diseases, mood disorder, pain and tobacco withdrawal symptom accompanied by cerebral ageing caused by an agonist ofα4β2 type central nicotinic receptor. SOLUTION: A compound represented by formula (I) [(n) is an integer of 1 to 6; R<SB>1</SB>and R<SB>2</SB>are each H, a 1 to 6C alkyl or an aryl-(1-6C) alkyl; R<SB>3</SB>and R<SB>4</SB>are each H or a 1 to 6C alkyl; R<SB>5</SB>and R<SB>6</SB>are each H, a 1 to 6C alkyl, a halogen, hydroxy, a 1 to 6C alkoxy, cyano, nitro, a 2 to 6C acyl, a 1 to 6C alkoxycarbonyl, a 1 to 6C trihaloalkyl, a 1 to 6C trihaloalkoxy or, amino which is substituted, if necessary]. COPYRIGHT: (C)2007,JPO&INPIT
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