| 发明名称 |
LIBRARY FROM TOXIN MUTANTS, AND METHODS OF USING SAME |
| 摘要 |
<p>This application relates to libraries of ABx toxin mutants, in which a peptide insert is introduced into the protease-sensitive loop of the A-chain sequence to alter the type of cells to which toxic species are delivered. Said libraries are used in the development of therapeutics targeted against specific cell types.</p> |
| 申请公布号 |
WO2007033497(A1) |
申请公布日期 |
2007.03.29 |
| 申请号 |
WO2006CA01581 |
申请日期 |
2006.09.26 |
| 申请人 |
UNIVERSITY HEALTH NETWORK;GARIEPY, JEAN;REVERS, LEIGH |
发明人 |
GARIEPY, JEAN;REVERS, LEIGH |
| 分类号 |
C07K14/245;C12Q1/18;C40B30/04;C40B40/10;G01N33/566;G01N33/58 |
主分类号 |
C07K14/245 |
| 代理机构 |
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