发明名称 |
Process for the synthesis of amorphous atorvastain calcium |
摘要 |
The invention relates to a new process for the synthesis of amorphous atorvastatin calcium, which consists of dissolving the salt of the formula (I) of atorvastatin acid formed with a basic amino acid (I); in a mixture of water and a water miscible organic solvent, adding an aqueous solution of a water soluble calcium salt to the solution and isolating the so obtained entirely amorphous atorvastatin calcium of high purity by filtration.
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申请公布号 |
US2007066835(A1) |
申请公布日期 |
2007.03.22 |
申请号 |
US20040550415 |
申请日期 |
2004.03.23 |
申请人 |
CZIBULA LASZLO;DOBAY LASZLO;PAPP EVA W;JUHASZ IDA D;BALINT SANDORNE |
发明人 |
CZIBULA LASZLO;DOBAY LASZLO;PAPP EVA W.;JUHASZ IDA D.;BALINT SANDORNE |
分类号 |
C07D207/337;A61P3/06;C07D207/34 |
主分类号 |
C07D207/337 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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