The invention provides compounds of formula I as described herein wherein Y is F, Cl or Br; or a pharmaceutically acceptable salt thereof. The compounds are effective antitumor agents. The invention also provides pharmaceutical compositions comprising a compound of formula I or a salt thereof, intermediates useful for preparing a compound of formula I, and therapeutic methods comprising administering a compound of formula I or a salt thereof to a mammal in need thereof.
申请公布号
WO2007030780(A2)
申请公布日期
2007.03.15
申请号
WO2006US35184
申请日期
2006.09.11
申请人
WAYNE STATE UNIVERSITY;HORWITZ, JEROME P.;POLIN, LISA;HAZELDINE, STUART T.;CORBETT, THOMAS H.
发明人
HORWITZ, JEROME P.;POLIN, LISA;HAZELDINE, STUART T.;CORBETT, THOMAS H.