发明名称 PHARMACEUTICAL TITANIUM DIOXIDE COMPOSITE MATERIAL OF WHICH PHARMACOLOGICAL EFFECT CAN BE ELIMINATED BY LIGHT IRRADIATION
摘要 PROBLEM TO BE SOLVED: To provide a titanium dioxide composite material which can be stably dispersed in an aqueous solvent, easily administered into a body, and in which the pharmacological effect of a therapeutic compound carried on the composite material can be eliminated by irradiation with light, and a dispersion product of the composite material. SOLUTION: The composite material is obtained by attaching the therapeutic compound to the titanium dioxide having a photocatalytic activity through a hydrophilic polymer. The composite material is stable in the aqueous solvent, and easily administered to the body. After the composite material is administered to the body, where the pharmacological effect of the therapeutic compound is not needed to be developed can be irradiated with light to induce the light excitation of titanium oxide at the site and decompose the therapeutic compound for reducing its adverse effect. COPYRIGHT: (C)2007,JPO&INPIT
申请公布号 JP2007063253(A) 申请公布日期 2007.03.15
申请号 JP20060171781 申请日期 2006.06.21
申请人 TOTO LTD;YOKOHAMA CITY UNIV 发明人 SONEZAKI SHUJI;KANEHIRA YUKITERU;OGAMI ARIYOSHI;SAKANISHI TOSHIAKI;KUBOTA YOSHINOBU
分类号 A61K47/48;A61K9/10;A61K31/704;A61K38/00;A61K47/02;A61K47/32;A61K47/38;A61P35/00 主分类号 A61K47/48
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