发明名称 Subcutaneous delivery system, process for the preparation of the same and use of the same for the treatment of cholinergic deficient disorders
摘要 The present invention relates to a subcutaneous delivery system comprising a biodegradable polymeric matrix and at least one of the pharmacologically active substances of general formula (I): wherein A represents an amino group -NH<SUB>2 </SUB>or an ammonium group -NH<SUB>3</SUB>+ or a residue of general formula (II): wherein each of X<SUB>1 </SUB>to X<SUB>5 </SUB>represents, independently, an hydrogen atom, a linear or branched C<SUB>1 </SUB>to C<SUB>6 </SUB>alkyl group, a linear or branched C<SUB>1 </SUB>to C<SUB>6 </SUB>alkyloxy group, a hydroxyl group -OH, an amino group -NH<SUB>2</SUB>, a primary or secondary C<SUB>1 </SUB>to C<SUB>6 </SUB>alkylamino group, a halogen atom, a nitro group -NO<SUB>2</SUB>; said substance being embedded into said matrix. It relates also to a process for its preparation and to its use for the preparation of a medicament.
申请公布号 US2007059369(A1) 申请公布日期 2007.03.15
申请号 US20040549167 申请日期 2004.03.15
申请人 MAUVERNAY ROLLAND-YVES;PORCHET HERVE;SCALFARO PIETRO;HEIMGARTNER FREDERIC;DUCREY BERTRAND;PFEFFERLE FRANCOIS;CAPANCIONI SERGIO;MC CORMICK MARK 发明人 MAUVERNAY ROLLAND-YVES;PORCHET HERVE;SCALFARO PIETRO;HEIMGARTNER FREDERIC;DUCREY BERTRAND;PFEFFERLE FRANCOIS;CAPANCIONI SERGIO;MC CORMICK MARK
分类号 A61K31/473;A61K;A61K9/00;A61K9/14;A61K9/20;A61K31/465;A61P21/00;A61P25/28;A61P39/00 主分类号 A61K31/473
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