| 摘要 |
FIELD: pharmacy, pharmaceutical technology. ^ SUBSTANCE: invention relates to a novel crystalline form VI of atorvastatin calcium, or its hydrates. Invention proposes a picture of powdery roentgen diffraction with value 2Theta determined by using Shimadzu XRD-6000 with K-radiation of copper at lambda = 1.5406 Å and with relative intensity >15%, 3.7365; 7.7200; 8.6985; 10.2185; 12.5933; 17.9103; 18.3600; 19.4031; 20.2800; 20.8200; 22.5122 and 25.5848. Also, invention describes methods for their preparing. Invention provides high purity, stability and solubility of proposed form. ^ EFFECT: improved and valuable properties of form VI. ^ 22 cl, 2 tbl, 6 ex |
