发明名称 |
SECRETED EPITHELIAL COLON STROMAL-1 POLYPEPTIDE, NUCLEIC ACID ENCODING THE SAME AND USE THEREOF |
摘要 |
<P>PROBLEM TO BE SOLVED: To provide a new polypeptide having diagnostic advantage or therapeutic advantage and a nucleic acid molecule encoding the polypeptide. <P>SOLUTION: The invention provides a separated nucleic acid molecule encoding a new secreted epithelial colon stromal-1 (Secs-1) polypeptide and containing a nucleotide sequence selected from a specific nucleotide sequence containing a DNA insert, its complement and a nucleotide sequence hybridizing to the above sequence under a moderately or highly stringent condition. The expression of Secs-1 polypeptide has a correlation to the hematopoietic stem cell maintaining performance of a stromal cell and is possible to be usable for the diagnosis and treatment of related diseases. <P>COPYRIGHT: (C)2007,JPO&INPIT |
申请公布号 |
JP2007054072(A) |
申请公布日期 |
2007.03.08 |
申请号 |
JP20060258117 |
申请日期 |
2006.09.22 |
申请人 |
AMGEN INC |
发明人 |
POLVERINO ANTHONY J;LUETHY ROLAND |
分类号 |
A01K67/027;C12N15/09;A61K38/00;A61K38/17;A61K48/00;A61P1/00;A61P1/02;A61P3/04;A61P3/10;A61P3/14;A61P7/00;A61P13/12;A61P19/00;A61P19/08;A61P19/10;A61P35/00;A61P43/00;C07K14/435;C07K14/47;C07K14/475;C07K16/18;C07K16/42;C07K16/46;C07K17/08;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/02;C12N15/12;C12P21/02;C12P21/08;C12Q1/02;C12Q1/68;G01N33/53;G01N33/566 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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