发明名称 |
Combination therapy for the treatment of obesity and diabetes and conditions related thereto and for the treatment of conditions ameliorated by increasing a blood GLP-1 level |
摘要 |
<p>The present invention concerns combination of an amount of a BRS-3 agonist with an amount of a dipeptidyl peptidase IV (DPP-IV) inhibitor such that the combination provides an effect in lowering a blood glucose level or in increasing a blood GLP-1 level in a subject over that provided by the amount of the BRS-3 agonist alone and by the amount of the DPP-IV inhibitor alone and the use of such a combination for treating or preventing obesity and diabetes and conditions related thereto and conditions ameliorated by increasing a blood GLP-1 level. The present invention also relates to the use of a G protein-coupled receptor to screen for GLP-1 secretagogues.</p> |
申请公布号 |
AU2006285393(A1) |
申请公布日期 |
2007.03.08 |
申请号 |
AU20060285393 |
申请日期 |
2006.04.26 |
申请人 |
ARENA PHARMACEUTICALS, INC. |
发明人 |
JAMES N. LEONARD;ZHI-LIANG CHU |
分类号 |
A61K45/06 |
主分类号 |
A61K45/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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