发明名称 |
Neural stem cells and use thereof for brain tumor therapy |
摘要 |
The present invention is based upon a surprising finding that stem cells, more particularly neural stem cells, can migrate throughout a brain tumor and track metastatic brain tumor cells. The invention provides a method for treating brain tumors by administering genetically engineered neural stem cells in an individual affected by brain tumors. The invention also provides a method of preparing genetically engineered neural stem cells and a composition comprising genetically engineered neural stem cells in a pharmaceutically acceptable carrier.
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申请公布号 |
US7186409(B2) |
申请公布日期 |
2007.03.06 |
申请号 |
US20010795675 |
申请日期 |
2001.02.28 |
申请人 |
NORTHEASTERN OHIO UNIVERSITIES COLLEGE OF MEDICINE |
发明人 |
SNYDER EVAN Y.;BREAKEFIELD XANDRA O.;ABOODY KAREN S.;HERRLINGER ULRICH;LYNCH WILLIAM P. |
分类号 |
A01N63/00;A61K35/12;A61K38/12;A61K48/00;C12N5/0797;C12N5/10;C12N15/63 |
主分类号 |
A01N63/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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