发明名称 IL4 ANTIBODY AND USE THEREOF
摘要 <p><P>PROBLEM TO BE SOLVED: To provide a high affinity IL4 antagonist which suppresses eosinophillic inflammation and can be used to treat, prevent or diagnose allergic reactions, and use thereof. <P>SOLUTION: The invention provides a composition containing monoclonal antibodies having a high titer for human IL 4, for use in diagnosing allergies and other conditions associated with excess immunoglobulin E production in a human. A sample of biological fluid is brought into contact with the monoclonal antibodies having a high titer for human IL4, and subsequently, the occurrence of binding between the monoclonal antibodies and human interleukin 4 is assayed. <P>COPYRIGHT: (C)2007,JPO&INPIT</p>
申请公布号 JP2007045831(A) 申请公布日期 2007.02.22
申请号 JP20060243117 申请日期 2006.09.07
申请人 SMITHKLINE BEECHAM CORP;SMITHKLINE BEECHAM PLC 发明人 HOLMES STEPHEN D;GROSS MITCHELL STUART;SYLVESTER DANIEL R
分类号 C07K16/24;G01N33/53;A61K38/00;A61K39/395;A61P37/08;C07H21/04;C07K16/46;C12N5/10;C12N15/02;C12N15/09;C12P21/08;G01N33/531;G01N33/577;G01N33/68 主分类号 C07K16/24
代理机构 代理人
主权项
地址