发明名称 |
Novel enterokinase cleavage sequences |
摘要 |
Novel enterokinase cleavage sequences are provided. Also disclosed are methods for the rapid isolation of a protein of interest present in a fusion protein construct including a novel enterokinase cleavage sequence of the present invention and a ligand recognition sequence for capturing the fusion construct on a solid substrate. Preferred embodiments of the present invention show rates of cleavage up to thirty times that of the known enterokinase cleavage substrate (Asp)<SUB>4</SUB>-Lys-Ile.
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申请公布号 |
US2007031879(A1) |
申请公布日期 |
2007.02.08 |
申请号 |
US20060542881 |
申请日期 |
2006.10.04 |
申请人 |
LEY ARTHUR C;LUNEAU CHRISTOPHER J;LADNER ROBERT C |
发明人 |
LEY ARTHUR C.;LUNEAU CHRISTOPHER J.;LADNER ROBERT C. |
分类号 |
C40B30/06;C07H21/04;C07K5/117;C07K7/06;C07K7/08;C12N1/21;C12N9/12;C12N15/74;C12P21/04;C40B40/10;C40B50/06 |
主分类号 |
C40B30/06 |
代理机构 |
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地址 |
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