NOVEL HETEROCYCLIDENE ACETAMIDE DERIVATIVE

摘要

Disclosed are a compound represented by the formula (I') below, a salt thereof, and a solvate of any of them. Also disclosed are a pharmaceutical composition containing such a compound as an active ingredient, and a TRPV 1 (Transient Receptor Potential Type I) receptor antagonist. [Chemical formula 1] (I') (In the formula, m, n and p respectively represent 0-2; q represents 0-1; R¹ represents a halogen, a hydrocarbon group, a heterocyclic group, an alkoxy group, an alkoxycarbonyl group, a sulfamoyl group, a CN group, an NO₂ group or the like; R² represents a halogen, an amino, a hydrocarbon group, an aromatic heterocyclic group or an oxo group; X₁ represents O, -NR³- or -S(O)r-; X₂ represents a methylene group, O, -NR³- or -S(O)r-; Q' represents a heteroaryl group, a heteroarylalkyl group, a substituted aryl group or aralkyl group; the cycle moiety represents an aryl ring or a heteroaryl ring; and the wavy line represents an E-form or a Z-form.)